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Russia completes clinical trials of COVID-19 vaccine

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Sechenov University in Moscow said it has completed clinical trials using human volunteers for the COVID-19 vaccine, Russian news agency TASS reports.

According to Sechenov University Center for Clinical Research on Medications head and chief researcher Elena Smolyarchuk, study data showed the vaccine candidate’s effectiveness.

“The research has been completed and it proved that the vaccine is safe. The volunteers will be discharged on 15 July and 20 July,” Smolyarchuk was quoted by the news agency.

Having spent 28 days in isolation, the 38 paid trial candidates will be placed under observation for six months after being discharged.

Last month, Russia granted authorisation for clinical trials of two formulations of the Covid-19 vaccine candidate, which was developed by the Gamaleya National Research Center for Epidemiology and Microbiology.

An intramuscular solution of the vaccine was tested at the Burdenko Military Hospital while Sechenov University assessed the vaccine in the form a powder for the preparation of an intramuscular solution.

The first stage of testing at the university commenced on 18 June in a group of 18 participants. The second group of the study involved 20 volunteers who were vaccinated on 23 June.

Institute for Translational Medicine and Biotechnology director Vadim Tarasov also told Russian news agency Sputnik that Sechenov University in a pandemic situation acted not only as an educational institution but also as a scientific and technological research center that is able to participate in the creation of such important and complex products as drugs.

“We worked with this vaccine, starting with preclinical studies and protocol development, and clinical trials are currently underway,” Tarasov stated.

Prior to the human trials, the vaccine was tested for its toxicity, safety, immunogenicity, and effectiveness in large and small animals at the Russian Defence Ministry’s 48th Central research institute.

Coronavirus

Covid-19 vaccine from Pfizer and BioNTech is more than 90 percent effective in the first analysis, company reports

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Pfizer and partner BioNTech said Monday that their vaccine against Covid-19 was strongly effective, exceeding expectations with results that are likely to be met with cautious excitement — and relief — in the face of the global pandemic.

The vaccine is the first to be tested in the United States to generate late-stage data. The companies said an early analysis of the results showed that individuals who received two injections of the vaccine three weeks apart experienced more than 90% fewer cases of symptomatic Covid-19 than those who received a placebo. For months, researchers have cautioned that a vaccine that might only be 60% or 70% effective. 

The Phase 3 study is ongoing and additional data could affect results.

Read more via statsnews.com

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EPL confirms eight positive COVID-19 tests

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The Premier League in England said on Monday that eight people had returned positive results in its latest round of COVID-19 tests conducted on players and staff last week.

The league said the individuals who had tested positive for the novel coronavirus would now self-isolate for 10 days.

“The Premier League can today confirm that between Monday, Oct. 12 and Sunday, Oct. 18, 1,575 players and club staff were tested for COVID-19. Of these, there were eight new positive tests,” the Premier League said in a statement.

A total of 42 people have tested positive for the virus in seven rounds of testing since the new campaign began on Sept. 12.

There have been more than 750,000 COVID-19 infections and over 43,000 deaths in the UK, according to a Reuters tally.

(Reuters/NAN)

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[#EndSARS Protests] Nigeria should prepare for increase in COVID-19 cases — FG warns

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Federal Government has warned that with the on-going #ENDSARS protests across the country, cases of COVID-19 will definitely increase in the coming weeks.

Issuing the warning in Abuja, the Chairman, Presidential Taskforce, PTF, on COVID-19 and Secretary to the Government of the Federation SGF, Mr. Boss Mustapha, said despite the appreciable success recorded so far in the fight against COVID-19, the ongoing protests might spark up a second wave of the virus.

He said:  “I can say it authoritatively that with the ongoing protests across the country, in the next two weeks the cases of COVID-19 would have increased. Each and everyone that attended the protests and did not put up any form of protection are likely going to spread the virus. When people contract the virus during the protest gathering, they will go back home and spread it.

“This is one of the reasons we must be extremely careful when we congregate because when you gather together in such an atmosphere where people don’t wear face masks or maintain social distance you are creating potential opportunities for carriers to spread the virus.

“So far we have done pretty well as a country but this protest is like a setback and we must avoid a situation where we will have resurgence. Countries that thought they have overcome are dealing with second wave. We are extremely lucky as a nation and we should be careful of any situation that can warrant second wave.”

Corroborating his views as reported by Vanguard, National Coordinator of PTF on COVID-19, Dr Sani Aliyu, said FCT and Lagos State have successfully tested one percent of their populations, while states such as Rivers, Plateau, Gombe were half way in achieving the one percent target.

“We urge other states to work hard in achieving this target of 1 percent testing because testing rate is still low in the country.  Through our various member MDAs, ‘’We have trained at least 17,000 health works in infection prevention and control, laboratory operation and case management.

“In partnership with Federal Ministry of Heath we have added over 7,000 beds in more than 130 treatment centres, 250 intensive care unit beds through support from donors and the private sector,’’ he said.

On his part, the Minister of State for Health, Adeleke Mamora, said the ministry has distributed ventilator and oxygen to all federal and state hospitals.

He disclosed that one of the challenges federal hospitals were facing was irregular power supply which often leads to breakdown of equipment and disruption of services, “We receive the management of power holding to discuss way of having regular power supply to our teaching hospital and medical centres, this partnership will reduce overhead cost of the hospital,’’ he said.

He said their experience with the management of the pandemic revealed that many of the victims died could have been saved if they had access to services on time, adding that, during their intervention in Kano, ambulances were deployed to evacuate people in critical condition to the hospital.

Meanwhile, President of the Nigeria Medical Association, NMA, Prof Innocent Ujah, disclosed yesterday that no fewer than 1,031 doctors in Nigeria have been exposed to coronavirus in the country, while 16 mortality cases were recorded as of October 8, 2020. According to him, this puts the mortality rate at 4.98 percent.

Speaking at a press conference in Lagos to announce the NMA 2020 Physicians’ Week, with the theme ‘’Strategy for health system recovery during the Covid-19 pandemic in Nigeria” and sub-theme: “Dental caries: The four-pronged fork.” Ujah said of the 1,031 cases, 321 were confirmed, while 16 doctors were lost in the battle against the virus.

Ujah, who expressed sadness over the deaths of  members, described their death as the prize they had to pay in obedience to the Hippocratic Oath of their profession. Stating that COVID-19 pandemic has exposed the inadequacies of health systems around the world,  the NMA president said many health systems across the world were overwhelmed by the pandemic due to inadequate emergency preparedness and response, largely due to inadequate human resources, infrastructural deficit and medical consumables, including personal protective equipment and other protective equipment.

He pointed out that most countries, such as Nigeria, were suffering due to gross under-funding of the health sector. He said:   “No disease has ever before laid bare the state of the country’s health sector like COVID-19. COVID-19 has revealed acute shortages of critical and lifesaving equipment such as ventilators and intensive care beds in our hospitals.”

Ujah added that the dire shortages of medical capacity has further put a spotlight on the poor state of health in Nigeria and distance to travel to ensure that health care was affordable and accessible to all citizens for Universal Health Coverage, UHC, to be achieved.

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